Human Postmeiotic Segregation 2 Exhibits Biased Repair at Tetranucleotide Microsatellite Sequences
نویسندگان
چکیده
منابع مشابه
Human postmeiotic segregation 2 exhibits biased repair at tetranucleotide microsatellite sequences.
The mismatch repair (MMR) system plays a major role in removing DNA polymerization errors, and loss of this pathway results in hereditary cancers characterized by microsatellite instability. We investigated microsatellite stability during DNA replication within human postmeiotic segregation 2 (hPMS2)-deficient and proficient human lymphoblastoid cell lines. Using a shuttle vector assay, we meas...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2009
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-08-3499